Human codon usage

Chris Upton cupton at uvic.ca
Thu Sep 21 13:51:13 EST 2000

> >
> Hi James:  it works well for yeast and e.coli but NOT for humans.
> Humans do not show increasing codon usage bias with gene expression
> levels.  Local G+C content variation seems to be the dominant factor in
> different usage of codons in human genes.
> Des Higgins
> Sent via Deja.com http://www.deja.com/
> Before you buy.

  Do you have any references for this observation?
I've always wondered about it....   you see many AT rich viruses
replicating very nicely in human cells!

  Chris Upton
Dept Biochemistry and Microbiology
University of Victoria
Victoria BC

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