The program MSPCrunch may do what you want. However, if the blast searching
is also batched, you can specify the e-value cutoffs in the blast client,
blastcl3 or blastall. In the scenario that you want to update the e-value
for the updated search, well, this value should be accurate given the search
space and lengths of the sequences; the computed e-value doesn't need to be
"fixed".
Bob
"Gary Williams"
> Has anyone got a good way of taking two blast output files (e.g. one
> from a search done on the previous release of the full Genbank/EMBL and
> the second one from a search of the updated entries in the latest
> release) and merging them so that the statistics (especially E value)
> are updated accordingly.