HI,
Even though the programe mentioned below is for a macintosh you might find
it usefull:
Lines&Kinetics: a graphic tool to deal with linear regressions and enzyme
kinetics.
Manuel G. Claros, Francisco M. Cánovas
Laboratorio de Bioquímica y Biología Molecular, Facultad de Ciencias e
Instituto Andaluz de Biotecnología, Universidad de Málaga, 29071 Málaga,
Spain.
There is an article describing the program on embnet.news vol5, no.1. If you
want to read the article please point yur browser to
www2.ebi.ac.uk/embnet.news/ and look for vol5, no.1
Also, searching the biocatalog at the EBI
(http://www.ebi.ac.uk/biocat/biocat_ebi.html) I found:
DynaFit
AC BC00537
NAME DynaFit
DOMAIN Metabolic regulation
DOMAIN Enzyme kinetics; Equilibrium binding
SERVER http://www.biokin.com/dynafit/index.shtml
DESCRIPTION The main purpose of the program DynaFit is to perform
DESCRIPTION nonlinear least-squares regression of chemical kinetic,
DESCRIPTION enzyme kinetic, or ligand-receptor binding data.
DESCRIPTION The experimental data can be either initial reaction
DESCRIPTION velocities in dependence on the concentration of
DESCRIPTION varied species (e.g., inhibitor concentration vs. velocity),
DESCRIPTION or the reaction progress curves (e.g., time vs.
DESCRIPTION absorbance), or the composition at equilibrium in dependence
DESCRIPTION on the total concentrations (e.g., protein-DNA complex
DESCRIPTION concentration vs. total protein).
AUTHOR Petr Kuzmic
RA Kuzmic, P.
RT "Program DYNAFIT for the Analysis of Enzyme Kinetic Data:
RT Application to HIV Proteinase"
RL Anal. Biochem. 237:260-273(1996)
ADDRESS Petr Kuzmic, Ph.D.
ADDRESS B i o K i n Consulting
ADDRESS P.O. Box 8336
ADDRESS Madison, WI 53708
ADDRESS U.S.A.
CONTACT Petr Kuzmic : pkuzmic at biokin.com
SITE WWW Server at URL http://www.biokin.com/dynafit/index.shtml
OS DOS, Windows-95/NT, Macintosh, Unix (IRIX,AIX,OSF)
LANGUAGE Fortran
VOLUME 2 MB
REQUIRES Fast processor (100 MHz), Intel or PowerPC for desktop
platforms
COMMENTS The program is distributed with many example problems.
Georg Lipps wrote in message <35657d1d.21185396 at newsserv.uni-bayreuth.de>...
>Hello everybody,
>>I' m looking for a software (free or shareware) to calculate enzyme
>kinetics (Km, Ki, Hill plot, etc.). Does anybody knows a good Windows
>based programm which performs these calculations.
>>Thanks in advance,
>>Georg Lipps
>>P.S.: Please email directly as well, thanks.
>
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