Alignment program DIALIGN 2 available

Burkhard Morgenstern morgenst at gsf.de
Wed May 20 06:12:46 EST 1998

DIALIGN 2 available

We would like to announce a new release of the multiple 
alignment program DIALIGN.

DIALIGN relies on comparing whole segments of the sequences 
instead of comparing single residues. Pairwise as well as 
multiple alignments are constructed from gapfree pairs of 
segments (so-called `diagonals'). 
DIALIGN does not use any gap penalty, thus avoiding this 
critical parameter. Consequently, the program is able to 
detect isolated local homologies that can not be detected
by standard multiple alignment methods. 

An online version of the program is available at the 
Bielefeld University Bioinformatics Server (BiBiServ) 

without previous limitations, i.e. large data sets can be 
aligned and DNA as well as protein sequence alignment is 
now possible. 

In addition, executables for various platforms are available at

If you have any problems, questions, or comments concerning
DIALIGN, please let us know!

  Burkhard Morgenstern
P.S. Special thanks to Ashok Aiyar for all his help!  


Dr. Burkhard Morgenstern
GSF - National Research Center for Environment and Health
Institute of Biomathematics and Biometry
Ingolstaedter Landstr. 1
85764 Neuherberg 

email: morgenst at gsf.de

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