On 17 Mar 1998 12:56:14 -0500,
Allan Strand (astrand at linum.cofc.edu) wrote:
>I'm looking for software that will align multiple nucleic acid
>sequences based upon their translations into amino acid sequences.
>>That is, I would like the input and output of the algorithm to be
>nucleic acid coding sequences, but I want the actual alignment to be
>determined by the amino acid sequence implied by these NA sequences.
You should take a look at Burkhard Morgenstern's program DIALIGN.
It does exactly what you would like it to. Binaries are available
for a number of Unix platforms from:
ftp://ariane.gsf.de/pub/unix/dialign
In addition, because the GNU C compiler has been ported to Win95/WinNT,
it would not be difficult to make binaries available for those operating
systems as well.
Ashok
--
Ashok Aiyar, Ph.D.
McArdle Laboratory for Cancer Research
aiyar at ebv.oncology.wisc.edu
