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Pfam release 3.3

Ewan Birney birney at sanger.ac.uk
Mon Dec 7 14:31:41 EST 1998



                ANNOUNCING PFAM RELEASE 3.3
                ===========================

Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models.
Pfam families contain functional annotation and cross-references to
other databases.  Query sequences can be searched against the Pfam
library of profile hidden Markov models at the web sites below.

Pfam 3.3 contains 1390 families.  57% of proteins in SWISSPROT 35
and TrEMBL 5 have at least one match to a Pfam family.

The changes between Pfam release 3.3 and Pfam release 3.2 are:

         46 new families have been added.

For interactive access and searching see URLs

               http://www.sanger.ac.uk/Software/Pfam/
               http://pfam.wustl.edu/
               http://www.cgr.ki.se/Pfam/

The release is also available in flat file by anonymous ftp:

               ftp://ftp.sanger.ac.uk/pub/databases/Pfam/
               ftp://ftp.genetics.wustl.edu/pub/Pfam/

The Pfam HMM library is compatible with HMMER2 software, available
from
	       http://hmmer.wustl.edu/


___________________
The Pfam consortium
December 1998







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