Dave Kristofferson (kristoff at NET.BIO.NET) wrote:
: I'm thinking about setting up an in-house BLAST server on a limited
: budget and was wondering what kind of performance people are getting
: out of Linux machines these days. I've received some attractive
: quotes on 600 MHz Alpha and dual 450 MHz Pentium II systems with 1 GB
: of RAM in the $6,000 - $8,000 range. I'd be interested in hearing
: people's experiences with similar systems.
: Dave Kristofferson
Alpha works great if you compile using DEC CC under Digital Unix then use the
executable. Not so good complied with GCC under Linux. About 30% slower
for a start. Also there seem to be some probs. with the maths libraries
and PSI-BLAST as opposed to BLAST crashes randomly. (BLAST also crashes,
but there is a fairly straightforward fix (one of the maths calls
causes a numeric underflow in calculating E from the bit-score).
Hope that helps,