Anthony Ting wrote:
> Is anyone aware of a program that translate a protein sequence
> into a nucleotide sequence given a specific codon usage table?
The SEALS command
wimklein
can do reverse translations under all known genetic codes. See
http://www.ncbi.nlm.nih.gov/Walker/SEALS/index.html
and
http://www.ncbi.nlm.nih.gov/Walker/SEALS/info/readmes/wimklein.html
The reverse translation uses ambiguity codes, and does not address
the question of likely codon usage.
I'd be happy to add the ability to reverse translate accounting for
user-supplied codon-usage data, perhaps in the form of a separate
tool that could redefine any ambiguous sequence according to a codon-
usage table.
What is the typical input format for the codon-usage table?
R