WinASCD is a program to analyze single channel and whole-cell pClamp
data
(Clampex, Fetchex, AxoTape).
It is a 32-bit (WIn95/NT) updated version of an original DOS program
that I
started writing more than 10 years ago.
It includes the following main features:
1. a data correction module for
baseline restoration (drift correction)
background subtraction (correction for leak and capacitative
current)
2. a module for calculating average and peak currents
ensemble averaged current
avg current for continuous data
avg and peak current for triggered data
3. a module to construct linear combinations of records belonging to the
same or different files
4. a module to fit sum of exponentials or a kinetic model to indivudual
current traces, ensemble averaged currents and composed records
5. a module for the Analysis of Single Channel Data, including
Amplitude histogram construction and fit with Gauss peaks
Kinetic Analysis: idealization, dwell time histograms, first
latencies,
burst analysis, analysis of the number
of events
6. a module for the analysis of current fluctuations, including current
variance analysis and FFT.
Each window (graphical or text) can be printed (not a screen dump) or
saved
as a TAB delimited ASCII file for import in e.g. a presentation software
package.
A demo version of the program in which output is disabled is available
from
ftp://cc5.kuleuven.ac.be/pub/droogmans/winascd.zip
--
Guy Droogmans
Laboratorium voor Fysiologie
Campus Gasthuisberg, KU Leuven
B-3000 Leuven (Belgium)
Tel 32 16 345 726
Fax 32 16 345 991
