In article <5b0sa7$k0t at erika.cica.es>, bb1rofra at uco.es (Antonio Rodriguez Franco) writes:
>I am trying to raise polyclonal antibodies using a short oligopeptide
>stick to albumin.
>>Is there any reliable software in which to test the antigenicity and
>surface probability of my sequence?
There is the program ANTIGENIC which is part of the EGCG package (which
means you also have to have GCG).
ANTIGENIC
ANTIGENIC looks for potential antigenic regions using the method of
Kolaskar.
ANTIGENIC
DESCRIPTION
Antigenic predicts potentially antigenic regions of a protein
sequence, using the method of Kolaskar and Tongaonkar (1990); FEBS
Letters 276:172-174 "A semi-empirical method for prediction of
antigenic determinants on protein antigens."
Regards,
David Mathog
mathog at seqaxp.bio.caltech.edu
Manager, sequence analysis facility, biology division, Caltech