We would like to announce the availability of
an alignment program called
DIALIGN
*******
DIALIGN is a completely novel program for pairwise
as well as multiple alignment of nucleic acid and
protein sequences. It is especially suited to detect
local similarities in otherwise completely unrelated
sequences and it does not employ any kind of gap penalty.
The method is described in
B. Morgenstern, A. Dress, T. Werner:
Multiple DNA and protein sequence alignment based on
segment-to-segment comparison
Proc. Natl. Acad. Sci. 93 pp. 12098 - 12103 (1996)
DIALIGN executables for various UNIX platforms (DEC,
SGI, CONVEX, HP, SUN) together with a detailed user
guide, online help and a test example are available at
http://www.gsf.de/biodv/dialign.html
or via ftp:
ftp://ariane.gsf.de/pub/unix/dialign
More detailed information on DIALIGN is available at
our web page. If you have any questions, please feel
free to contact us by e-mail.
Burkhard Morgenstern
----------------------------------------------------------
Dr. Burkhard Morgenstern
GSF - National Research Center for Environment and Health,
Institute of Biomathematics and Biometry
Ingolstaedter Landstr. 1,
85764 Neuherberg,
Germany
morgenstern at gsf.de