In article <lfliegel-020596150217 at fliegel-2.cvascular.med.ualberta.ca>,
lfliegel at gpu.srv.ualberta.ca (L. Fliegel) wrote:
> If anyone knows of any good software or programs which can be used for
> analysis of multiple inhibitors can they give me a call at the address
> below. (Mac versions especially). We have have examined the effect of
> inhibitors on a cell type which has 2 forms of a protein, a resistant and a
> sensitive protein. We would like to try and fit the data and analyze
> inhibitory constants presumably by using something that can fit data to
> nonlinear least squares regression. We would be willing to purchase
> software for this purpose.
>>lfliegel at gpu.srv.ualberta.ca
If you are intereted in simulating the kinetic mechanism, I strongly
recommend KinSim, which is a VAX program, or its Mac version, HopKinSim,
which was ported to Mac by people at Johns Hopkins U. This is a very nice
program and is a postcard ware.
Unfortunately, I don't have the URL on hand, but I found it with Web
search. Give it a try. If you have difficulty, E_mail me.
Good luck.
