It has become vitally important for molecular biologists to be able to rapidly
identify new sequences similar to theirs. Database searching programs such as
BLAST are very useful in this regard, but, with the vast amount of data being
produced, doing searches and browsing rather bulky result files to find novel
similarities is a very tedious task which must be repeated over and over again,
ideally as soon as new sequences have been incorporated into the database of
Honestly, haven't you ever dreamt that someone would keep the watch for you?
That's exactly what DBWatcher can do for you when run daily :
1) Search a database for similarities to your sequence(s)
when there has been an update since last search.
2) Browse results to find novel similarities.
3) Send these novel similarities by e-mail to you and/or
your colleagues and collaborators.
And if you do not have a direct access to BLAST programs and databases, don't
worry. You may ask a colleague or a collaborator to run DBWatcher for you and
you'll automatically receive the results in your e-mail box. And your colleague
doesn't even have to receive the results if he doesn't want to. This might suit
well a local area network with a server dedicated to sequence analysis or even a
BLAST searches e-mail or WWW server (why not? is anybody interested in setting
At the moment, DBWatcher jobs can only be managed by hand or with SetDBWatcher,
which takes care of everything in a very user-friendly way thanks to its GUI.
SetDBWatcher is distributed along with DBWatcher and requires the Vibrant NCBI
ToolKit and Motif libraries.