Does anyone know of any shareware out there that will analyze the
stability of DNA loop structures (i.e. up 40 bp). Specifically I am
looking for imperfect palindrome analysis. I need output in terms of
stability (dG, Tm) and hopefully graphical representation.
Current primer analysis programs don't seem to recognize imperfect
palindromes that are known to form loops (i.e. 1 bp mismatch).
Thanks,
dgebow at hsph.harvard.edu