Software and details:
http://s27w007.pswfs.gov/syd
Syd simulates crossings in a 3 generation pedigree of
4 grandparents, 2 parents, 1-500 progeny. It outputs
a data file which can be used as input --with some
adjustments-- for standard linkage mapping programs.
Here's the abstract prepared for Plant Genome IV:
Syd simulates the genetics involved in a three-generation
outbred pedigree with codominant alleles and produces a
synthetic data file which can be analyzed with conventional
linkage software. The simulation can be parameterized
using a configuration file that allows control over
chromosome number, population size, loci per chromosome,
chiasmatic frequency, and allelic distribution in simulated
crosses. The data can be produced with phase known or
unknown. Multiple pedigrees of the same species can be
created and the data sampled and resampled. Syd allows
hypotheses about preparation of laboratory data for linkage
analysis to be tested in a controlled manner.
Consider this a ``beta'' release. Syd is written in C and has
compiled and run under SunOS and AIX; it should work on other
Unix-like systems.
--bks
--
Bradley K. Sherman | Institute of Forest Genetics
bks at s27w007.pswfs.gov | P.O. Box 245
510-559-6437 FAX:510-559-6440 | Berkeley, CA 94701 USA
<a href="http://s27w007.pswfs.gov/~bks/">Dendrome Project</a>
