In article <48sku3$815 at mserv1.dl.ac.uk>,
jpleiss at TEBIO1.BIOLOGIE.UNI-STUTTGART.DE (Juergen Pleiss) wrote:
>Dear colleagues,
>is there any programm available for the generation of restriction sites in
>a given nucleotide sequence? I have to introduce several restriction sites
>in a nucleotide sequence by changing the codon usage without altering
>the amino acid sequence. Introducing these sites by hand is a very tediuos
>work. So, I would like to know if someone knows a computer program doing
>this work.
>Juergen
If you have access to GCG, the mapping programs have a "/silent" option
(-silent on Unix) which will do exactly that, find silent restriction sites.
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