In article <ldcheu-2704950009010001 at ldcheu.monsanto.com>,
ldcheu at ccmail.monsanto.com (Duncan Cheung) says:
>
>We are interested in a computational molecular biologist to design and
>implement a computer program (Mac friendly) that will allow the input of
>Southern results from genomic DNA to determine copy number and insert
>integrity of complicated insertion events from a transgenic event (eg.,
>the genes were inserted into genomic DNA using plasmid DNA).
>
>The ideal system will allow for the input of the known plasmid map with
>results. The output (what the computer will produce) is a linkage map
>that elucidates possible gene order and integrity (missing or rearranged
>pieces).
I'm pretty sure that Dave Waddington wrote some code to do this a couple
of years ago. Try doing a lit. search using Waddington and Burt as the
authors.
--
Andy Law
( Andy.Law @ bbsrc.ac.uk )
( Big Nose in Edinburgh )