ANNOUNCING THE AVAILABILITY OF PROMOTER SCAN version 1.60 for UNIX:
PROMOTER SCAN Version 1.60 for UNIX is now available. The program for
IBM PCs is NOT YET READY, and will be announced at a later date.
Please DO NOT send requests to 'send the PC version when ready'. It
will be announced soon.
Improvements in UNIX version 1.60 (over version 1.50) are:
1) The TATA box prediction has been improved, recognizing
approximately 10% more TATA boxes. Also, the TATA box is now used to
predict the Transcription Start Site (TSS). In our test set, PROMOTER
SCAN reports that 72% of recognized promoters contained TATA boxes;
and of those, the TSS is reported to within +- 10 bases of the actual
TSS. PROMOTER SCAN will recognize about 70% of primate promoter
sequences, and correctly report the TSS within 10 bases of the actual
TSS in 50% of primate promoter sequences, with a false positive
promoter prediction rate of about 1 in 17,200 non-promoter bases.
2) PROMOTER SCAN now reports the signals that it uses in determining a
promoter sequence. The name of the binding factor, its location,
strand, and significance weighting are reported (the weighting is used
only in discriminating promoter sequences from non-promoter sequences
and is NOT related to the overall quality of the signal, or as a
measure of it's being an actual binding site or not).
For information on how to obtain the latest copy of PROMOTER SCAN,
send requests to danp at biosci.cbs.umn.edu
__________________________________________________________
Dan S. Prestridge, Ph.D. E-mail: DANP at BIOSCI.CBS.UMN.EDU
Director Telephone: (612) 625-3744
Advanced Biosciences Computing Center Fax: (612) 625-5780
University of Minnesota
1479 Gortner Ave.
St. Paul, MN 55108
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