We are interested in a computational molecular biologist to design and
implement a computer program (Mac friendly) that will allow the input of
Southern results from genomic DNA to determine copy number and insert
integrity of complicated insertion events from a transgenic event (eg.,
the genes were inserted into genomic DNA using plasmid DNA).
The ideal system will allow for the input of the known plasmid map with
known restriction sites and characterized genes as well as the Southern
results. The output (what the computer will produce) is a linkage map
that elucidates possible gene order and integrity (missing or rearranged
pieces).
