software for Solvent Accessible Surface of Proteins

Mark Israel misrael at scripps.edu
Sat Nov 12 09:30:06 EST 1994

In article <39u5ka$bej at newshost.lanl.gov>, pxc at mendel.lanl.gov (Paolo Catasti) writes:

> Is there anybody who has or knows the site to have access to public software
> for Solvent Accessible Surface of Proteins?

   A search of the archives at gopher.bio.net turned up the following:


Newsgroups: bionet.xtallography
From: d.love at dl.ac.uk (Dave Love)
Organization: SERC Daresbury Laboratory, Warrington, UK
Message-ID: <D.LOVE.93Aug10115556 at dlpx1.dl.ac.uk>
Date: 10 Aug 93 10:55:56 GMT
Lines: 2

The CCP4 suite (ftp to ccp4.dl.ac.uk) also has technology for solvent


Newsgroups: bionet.software
Subject: Re: Wanted : GRASP - Molecular Surfaces
From: dalke at uxa.cso.uiuc.edu (Andrew Dalke)
Organization: University of Illinois at Urbana
Date: 22 Jul 1994 00:01:35 GMT
Message-ID: <30n28v$kg5 at vixen.cso.uiuc.edu>

In <9855 at eagle.ukc.ac.uk>, pjg1 at ukc.ac.uk (P.J.Gane) writes:

> I'm looking for the Molecular Surface Display program GRASP.

  I suggest anonymous ftp to cumbnd.bioc.columbia.edu in the directory
/grasp.  However, there is no public domain version of grasp.  There
is a very stunted demo version, which you can use to play around with
a few structures.  Read the README in that directory for more


Newsgroups: bionet.xtallography
From: raman at BIOC01.UTHSCSA.EDU (C.S.RAMAN)
Message-ID: <9308060159.AA04494 at bioc01.uthscsa.edu>
Date: 6 Aug 93 01:59:14 GMT

I just came across the following package, that might be of use to all
those interested in Protein and Nucleic Acid structure.


The MSP suite is made up of 8 different programs!

Here is a brief description:

* MSP computes Solvent-accessible surfaces of Protein and Nucleic Acids.

* Different types of surfaces can be generated with MSP:
Polyhedral surfaces made up of triangles, pixel maps of rendered
surfaces, piece-wise quartic molecular surfaces and Dot surfaces.  

* Cavities in Proteins are identified and accurate solvent-accessible
areas and Solvent-excluded volumes are also calculated.

* MSP also provides methods for estimating protein surface curvature and
for plotting surfaces with hidden-line elimination.

A description of MSP appeared in the June issue of J. Mol. Graphics. 
Vol. 11, 139-141 [1993].

MSP is written in C.

Those interested in obtaining MSP should contact the author Dr. Michael
Connolly via email:  connolly at netcom.com         


misrael at scripps.edu			Mark Israel

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