Jason L. Buberel (jbuberel at uiuc.edu) wrote:
: Could someone please let me know if there is a simple (straighforward) way
: to ask GenBank (or a similar service) to compare sequence homology for me
: if I give it the names of several related genes (or same gene between
: different species). We are trying to find conserved areas among the
: cytochrome enzyme genes. We have played with the GenBank web site,
If you have a WWW browser, you should find out more about
ENTREZ. The ENTREZ service is now available on the web:
http://www.ncbi.nlm.nih.gov/Search/Entrez/index.html
You have to register your machine (IP address) to get full
function from Netwrok-ENTREZ or WWW-ENTREZ, but once you do, you
will have a world of info at your fingertips.
ENTREZ has not only gene and protein sequences, but also a
large subset of medline (articles pertaining to genes and proteins
are there, clinical trials and such are not).
ENTREZ also has a VERY POWERFUL "neighboring" function.
NCBI has already compared every sequence to every other one, so if
you select a gene, protein or medline abstract and click the
"neighbors" button, ENTREZ will show you the other genes, proteins
or abstracts that are most similar to the one you selected.
--
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* Brian Foley * If we knew what we were doing *
* Molecular Genetics Dept. * it wouldn't be called research *
* University of Vermont * *
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