Brian Foley (brianf at med.uvm.edu) wrote:
> Jason L. Buberel (jbuberel at uiuc.edu) wrote:
> : Could someone please let me know if there is a simple (straighforward) way
> : to ask GenBank (or a similar service) to compare sequence homology for me
> : if I give it the names of several related genes (or same gene between
> : different species). We are trying to find conserved areas among the
> : cytochrome enzyme genes. We have played with the GenBank web site,
> If you have a WWW browser, you should find out more about
> ENTREZ. The ENTREZ service is now available on the web:
>http://www.ncbi.nlm.nih.gov/Search/Entrez/index.html
> You have to register your machine (IP address) to get full
> function from Netwrok-ENTREZ or WWW-ENTREZ, but once you do, you
> will have a world of info at your fingertips.
Thanks for pointing out this information, Brian. I want to clarify,
though, that registration is _not_ required to use WWW-Entrez, although
it is required for Network Entrez. Information regarding both of these
services, as well as the Entrez CD-ROM is available by following the
"Entrez Browser" hypertext link from the above WWW page.
Information about Network Entrez is also available by viewing the file
ftp://ncbi.nlm.nih.gov/entrez/network/README or by writing to
net-info at ncbi.nlm.nih.gov.
> ENTREZ has not only gene and protein sequences, but also a
> large subset of medline (articles pertaining to genes and proteins
> are there, clinical trials and such are not).
> ENTREZ also has a VERY POWERFUL "neighboring" function.
> NCBI has already compared every sequence to every other one, so if
> you select a gene, protein or medline abstract and click the
> "neighbors" button, ENTREZ will show you the other genes, proteins
> or abstracts that are most similar to the one you selected.
> --
> ********************************************************************
> * Brian Foley * If we knew what we were doing *
> * Molecular Genetics Dept. * it wouldn't be called research *
> * University of Vermont * *
> ********************************************************************
- Jonathan
Jonathan Epstein epstein at ncbi.nlm.nih.gov
National Center for Biotechnology Information Phone: (301)496-2475
National Library of Medicine Building 38A, Room 8N805
National Institutes of Health 8600 Rockville Pike
Bethesda, MD 20894
