Probe/primer software/hardware questions

Potter Wickware wick at netcom.com
Fri Jan 28 02:52:53 EST 1994

I don't see why you need a UNIX machine to do this kind of work.  Why not 
a 486 clone?  With the $$$ you save you can get a good commercial primer 
design package like National Bioscinece's Oligo program (they have an 800 
#), and still have enough left over to buy a comprehensive analysis 
program like DNA Star or the Hitachi DNASIS package.  

P Wickware, Oakland, CA

On Thu, 27 Jan 1994, Debbie Lonergan wrote:

> Hi,
> We have a small research group studying the molecular ecology of
> sediments, soils and aquifers. At present, we're designing
> probes and primers based on 16s rRNA sequences and are considering
> purchasing a UNIX workstation to assist us in this task. We've 
> done a cursory survey of public domain software, but remain a little
> confused. Does anyone have suggestions for the appropriate suite
> of software for probe and primer design and sequence comparisons? 
>  Any suggestions for the best platform to run these on?  Any help'd
> be greatly appreciated!
> Thanks,
> -Debbie
> -- 
> Debra J. Lonergan				lonergan at stress.er.usgs.gov
> U.S. Geological Survey         (703) 648-5987 | FAX (703) 648-5274
> Mailstop 430, National Center  "Sometimes you're the bug.
> Reston, Virginia 22092          Sometimes you're the windshield."

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