I am looking for a computer program that calculates the Tm of
oligonucleotides using a nearest neighbor algorythm . It is referenced in
Nucleic Acids Research (1989) 17,8543-8551. In the paper it says to write
to NBI, 725 Tower Drive, Hamel, MN 55340. I did that, but they have moved
and their forwarding address has expired.
This program is built into some oligonucleotide sequencers, and is useful
for predicting Tm's for PCR experiments.
Thanks.