heuss at urz.unibas.ch wrote:
: I am looking for a program which is capable of predicting the so called
: "coiled-coil" motifs in protein sequences.
There is such a program available, and installed at our VMS site, in the
'GCGE' package from Peter Rice (this is, you must have access to GCG, and
the extensions of GCG installed on the same computer. )
Example run:
'yogi > pepcoil
PEPCOIL identifies potential coiled-coil regions of protein sequences
using the algorithm of Lupas A, van Dyke M & Stock J; Science 252:1162-4 (1991).
PEPCOIL of what protein sequence ? swissprot:Lam1_Human
Begin (* 1 *) ?
End (* 585 *) ?
What shall I call the output file (* Lam1_Human.Coil *) ?
Maximum score 2.137 (probability 1.000) at residue 158
Driver instructions for a COLORWORKSTATION are now being sent to Xwindowdevice:.
PEPCOIL of swissprot:Lam1_Human August 25, 1994 10:40
using a window of 28 residues
Other structures from 1 to 24 (24 residues)
Max score: 1.350 (probability 0.49)
Prediction starts at 25
25..68 frame 6..7
69..219 frame 7..3
Probable coiled-coil from 25 to 219 (195 residues)
Max score: 2.137 (probability 1.00)
Other structures from 220 to 281 (62 residues)
Max score: 1.348 (probability 0.48)
Prediction starts at 282
282..333 frame 6..1
334..389 frame 5..4
Probable coiled-coil from 282 to 389 (108 residues)
Max score: 1.666 (probability 1.00)
Other structures from 390 to 585 (196 residues)
Max score: 1.266, Max probability 0.16
Regards
Reinhard Doelz
Biocomputing
Biozentrum der Universitaet
heuss at urz.unibas.ch wrote:
~~~~~~
: email: heussch1 at fmi.ch ~~~
--
+---------------------------+-------------------------------------------+
| Dr. Reinhard Doelz | Tel. x41 61 2672247 Fax x41 61 2672078 |
| Biocomputing | electronic Mail doelz at urz.unibas.ch |
|Biozentrum der Universitaet+-------------------------------------------+
