Software for drawing dendrograms from gel lane patterns?

John Nash nash at nrcbsa.bio.nrc.ca
Sat Aug 13 18:46:44 EST 1994

In article <32gqp6$g09 at mozo.cc.purdue.edu>,
Peter M. Muriana <muriana at aclcb.purdue.edu> wrote:
>Hi netters, 
>Does anyone know of public domain software (or commercial) for coming up 
>with dendrograms of similarity coefficients (or genetic distance?) from
>say, SDS-PAGE protein gel patterns or DNA RFLP analysis?


I've been on the net since 1989, and it's my first "me-too" post I
believe.  I'd better temper it with some information.

Would using Nei and Li's "index of similarity" to create a matrix and
then passing it through one of Phylip's programs like "neighbor" do?
If so, I wrote some C code to passage gel mobilities or fragment sizes
through Nei and Li's algorithm and construct a matrix ready for
"neighbor".  I could post it (might have to re-code it for Suns,
though, they seem to prototype funny - I use SGIs & PCs) if you're
interested, and leave it up on my WWW server for posterity.


John Nash                          | Email: nash at nrcbsa.bio.nrc.ca
Institute for Biological Sciences  | http://cansnd.cisti.nrc.ca/~nash/home.html
National Research Council of Canada|  for an eclectic collection of
All opinions are mine, not NRC's!  |  WWW molbio and other services.

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