Bengt Persson's prog 'tms-predict' is an information derived package
which he has shown to be able to detect all but 5 of the putative
trans-membrane regions in the swiss-prot database. It is based on
multiple sequence alignments (nominally from pileup in GCG).
Apparently it will be deposited on the EMBL server shortly (ftp to
felix.embl-heidelberg.de)
--
cheers,
Mike.