Rodrigo Lopez writes:
>I'm looking for DOS based programs for reading, editing and
>evaluating gels. Any help will be deeply appreciated.
Because of the memory segmentation problems inherent in DOS, there will
always be problems in writing large programs (or programs that need large
amounts of contiguous memory space, like this one). While there are
sophisticated ways around this, they are usually difficult, expensive,
and/or sufficiently ugly that a programmer will usually go to the Mac or
Unix OS to do this kind of program. To wit, NCSA Gelreader (of which you
are already aware), NCSA Image, NIH Image, (all for the Mac) and the
recently announced DNA/GUI (Unix), as well as number of others for unix.
That said, COMAP, a DOS program by Kay Hoffman
(KHOFMANN at cipvax.biolan.Uni-Koeln.DE), and available from most
bio-archives, provides a somewhat similar functionality as the
above-mentioned GelReader/ContigAsm for DOS machines. It is graphically
based, but uses DOS graphics, not Windows, and allows you to enter the
sizes of fragments and their mobilities for several enzymes, then
calculates the best map for the data. I've not used to any great extent,
but it's free and KH knows what he's talking/programming about.
Good Hunting...
Harry
Harry Mangalam Vox:(619) 453-4100, x250
Dept of Biocomputing Fax:(619) 552-1546
The Salk Institute 1' mangalam at salk-sc2.sdsc.edu
10010 N Torrey Pines Rd 2' hjm at salk-sgi.sdsc.edu
La Jolla CA 92037 3' mangalam at salk.bitnet
