Sheet of neurons simulation

David M. Senseman senseman at lucy.brainlab.utsa.edu
Fri Feb 19 08:32:04 EST 1993

In article <HUNTER.93Feb18144818 at work.nlm.nih.gov> Hunter at nlm.nih.gov writes:
>Francis Burton asks:
>  On behalf of a colleague, I am looking for software that can be used to
>  simulate large networks of connected neurons.
>Well, there are many public domain (or nearly so) neural network simulators
>out there that can do arbitrary topologies and update rules, at least with a
>little bit of programming.  IMHO, by far the best, both in terms of what
>comes with the system and how easy it is to program to meet specific needs,
>is the Xerion system from University of Toronto.  It has wonderful graphical
>interfaces (X windows) and runs on practically any Unix/X platform.  It is
>originally designed for use in machine learning and on artificial neural
>nets, but I think it offers a good possibility for adaptation to natural
>neural network simulation.

The original posting asked for something to run "on a PC." This sounds
unlikely to run on a PC even if it were running an X server.

However, if you can get a hold of a UNIX based workstation, (Sparc,
SGI, HP, IBM, etc), you might want to check out the Caltech Neurosimulator
called "GENESIS". GENESIS also sports a very nice X-windows based
front-end called "XODUS" (what else :).

Unlike Xerion which was primarily designed for "non-biological"
neural networks (i.e. back-propagation, etc.), GENESIS was
designed from the beginning to model REAL neurons. In fact GENESIS
has a group of commands that generates  "sheets of neurons"
and synaptically connects them to other sheets. Real HHK action
potentials, Calcium channels, dendrtitic spines, etc, etc...

I'm at home so I don't have all the details here, but if any
one is interested, they can contact me by E-Mail. 

Again this program MUST be run on a UNIX box that supports
X-Windows. If all you have is a PC, then this isn't for you.
David M. Senseman, Ph.D.              | Imagine the Creator as a low 
(senseman at lonestar.utsa.edu)          | comedian, and at once the world 
Life Sciences Visualization Lab       | becomes explicable.
University of Texas at San Antonio    |               H.L. Mencken 

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