Dear Bionetters,
Here is the newest readme file from the kinsim/fitsim program
archive at Washington University. All files can be obtained via anonymous
ftp to wuarchive.wustl.edu (128.252.135.4) or the fsp protocol. Hopefully
this will be of some use to those of you looking for an ADVANCED kinetic
simulation package. This is not your typical Lineweaver-Burke/Michaelis-Menten
type package but if you need to simulate multistep kinetics (eg. ordered Bi-Bi,
etc.) you might find this useful. Here's the readme file:
Welcome! You have entered the kinsim archive at Washington University. The
following subdirectories contain the kinetic simulation and fitting programs
described in Barshop et al. [Barshop, B. A., Wrenn, R. F. and Frieden, C.
(1983) Analytical Biochemistry 130, 134-145] (KINSIM) and in Zimmerle and
Frieden [Zimmerle, C. T. and Frieden, C. (1989) Biochem. J. 258, 381-387]
(FITSIM). These programs have been ported to the following platforms:
DEC VAX
Silicon Graphics Iris (IRIX)
IBMPC ( msdos, windows and OS/2)
Apple Macintosh
The organization for the archive is as follows:
kinsim/
docs/ documentation-see readme.doc in this directory
mac/ see readme.mac file in this directory
msdos/ see readme.pc file in this directory
sgi/ see readme.sgi file in this directory
vms/ Vax versions see readme.vms
General information about obtaining these programs is obtained from TIBS ((1993
) 18, 58-60). Since this article was published new versions of KINSIM have been
added.
The sgi version is courtesy of Dr. F. Rauschel's group.
winkin.zoo - Windows 3.x version of KINSIM,FITSIM and SFDISP ( a data display
program) courtesy of Dr. Bryce Plapp
hopKINSIM.hqx a more recent version of KINSIM from Johns Hopkins University
(courtesy of Dr. Tom Pollard). This program is a binhexed self-extracting
archive.
GENERAL COMMENTS
KINSIM AND FITSIM
The programs here, (KINSIM and FITSIM) are compatible with either VAX machines,
with IBM PCs , with Silicon Graphics (IRIS) or with MACs (KINSIM only). The
basic architecture for all programs is based on that originally developed by
Barshop et al.
For instructions of the operation of any of these programs, you should obtain
the documentation from the docs subdirectory. Fortran source codes are located
in the vms/vax version, in the IBM PC version and in the SGI version. The codes
can be obtained after downloding these versions to your computer.
Appropriate References: Please use these references in any publications that
rely on the use of either of these programs
For KINSIM
BARSHOP, B. A., WRENN, R. F. AND FRIEDEN, C. (1983) ANALYTICAL BIOCHEM.
130, 134-145.
For FITSIM
ZIMMERLE, C.T. AND FRIEDEN, C. (1989) BIOCHEM. J. 258, 381-387.
All the original programs used are copyrighted. Permission is granted for any
modifications.
Any requests for information or updates should be sent to
Prof. Carl Frieden
Department of Biochemistry and Molecular Biophysics
Box 8231
Washington University School of Medicine
St. Louis, Missouri 63110
Telephone: 314-362-3344
FAX:314-362-7183
E mail address: frieden at bcserv.wustl.edu
who has agreed to serve a a central resource
for these progams and their updates
Newsgroups: bionet.software
Subject: kinetic simulation
--
Eric R. Hugo, Postdoctoral Research Associate |eric at bcserv.wustl.edu
Dept. of Biochemistry and Molecular Biophysics|finger above for
Washington University School of Medicine |public key <--
Box 8231, St. Louis, MO 63110_________________| (314) 362-3342
