In article <2d0koqINNqdi at lifesci.ucsb.edu>, poole at lifesci.ucsb.edu (Stephen
> I saw a similar request a while back but didn't notice any responses, so
> I'll ask again. Does anyone know of enzyme kinetics software suitable for an
> undergraduate biochemistry lab course, preferably for Mac but UNIX also ok.
> I know of several DOS programs, but the class doesn't have access to
> appropriate machines. I'm aware of Don Gilbert's enzyme kinetics
> Hyperchem stack, but I'm not aware of any other Mac software. Thanks.
>> Steve Poole
>poole at molbio.ucsb.edu
You might just consider using one of the better general purpose scientific
graphing programs that will do regressions. We use SigmaPlot for the Mac,
but KaleidaGraph or Igor would also do fine. All of these will do the
linear regressions needed for Lineweaver-Burke, Hanes (& I forget the
others...) plots. They should also do the weighted linear regressions and
user-defined non-linear curve fits. The good thing about using a general
purpose program like these is that they will force the students to
understand the equations used in enzyme kinetics instead of just allowing
them to use the equations as some kind of black-box ;).
David McCaskill mccaskil at wsuvm1.csc.wsu.edu