T-cell epitopes

Dan Jacobson danj at merlot.gwu.edu
Tue Oct 20 09:13:27 EST 1992

In article <1992Oct20.124746.22749 at gserv1.dl.ac.uk> robertson at mpib-tuebingen.mpg.dbp.de (BRAIN ROBERTSON) writes:
>Dear Netters,
>Does anyone know of any software for the prediction of T-cell epitopes from
>peptide sequences?
>I have access to Mac, PC, VAX, SG & UNIX so the program format does not matter.
>Hope to hear from someone soon!
>	Brian Robertson
>	Max-Planck-Institut fuer Biologie
>	Abt. Infektionsbiologie
>	D74 Tuebingen, FRG.
>	Email robertson at mpib-tuebingen.mpg.de

Three programs which come to mind are Epiplot, Tsites, and Seqaid.
Epiplot and Tsites are programs devoted specifically for epitope
prediction, Seqaid is a general sequence utlity program with several
functions, one of which is epitope prediction.  Seqaid and Epiplot are
for PCs (DOS), Tsites has a Mac version and probably a DOS version.

You can ftp Epiplot from:

Host evolution.bchs.uh.edu

    Location: /pub/gene-server/dos
           FILE -rwxr--r--     129317  Sep 16 1991  epiplot.uue

You can ftp seqaid from:

Host fly.bio.indiana.edu

    Location: /molbio/ibmpc
           FILE -rw-r--r--     324175  May 14 1991  seqaidfd.uue

Host genbank.bio.net

    Location: /pub/dos
           FILE -rw-rw-r--       6167  Oct 26 1989  seqaid.doc
           FILE -rw-rw-r--     324175  Jul 14 1989  seqaidfd.uue

Host nic.funet.fi

    Location: /pub/sci/molbio/msdos
           FILE -rw-r--r--     251259  Feb  3 00:00  seqaid.exe
           FILE -rw-rw-r--     305448  Jun 23 1991  seqaid37.shar
           FILE -rw-r--r--      73370  Feb  3 00:00  seqaidfd.exe

There is no ftp site for Tsites that I know of, you can obtain it
for free by writing to:

MedImmune, Inc
19 Firstfield Rd.
Gaithersburg, MD 20878  (USA)

Kudos go to the authors and Dan Davison, Don Gilbert and Rob Harper for the
ftp sites.

Best of luck,

Dan Jacobson

danj at chablis.gwu.edu

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