In article <1992Oct20.124746.22749 at gserv1.dl.ac.uk> robertson at mpib-tuebingen.mpg.dbp.de (BRAIN ROBERTSON) writes:
>Dear Netters,
>>Does anyone know of any software for the prediction of T-cell epitopes from
>peptide sequences?
>>I have access to Mac, PC, VAX, SG & UNIX so the program format does not matter.
>>Hope to hear from someone soon!
>>Thanks,
> Brian Robertson
> Max-Planck-Institut fuer Biologie
> Abt. Infektionsbiologie
> D74 Tuebingen, FRG.
> Email robertson at mpib-tuebingen.mpg.de
Three programs which come to mind are Epiplot, Tsites, and Seqaid.
Epiplot and Tsites are programs devoted specifically for epitope
prediction, Seqaid is a general sequence utlity program with several
functions, one of which is epitope prediction. Seqaid and Epiplot are
for PCs (DOS), Tsites has a Mac version and probably a DOS version.
You can ftp Epiplot from:
Host evolution.bchs.uh.edu
Location: /pub/gene-server/dos
FILE -rwxr--r-- 129317 Sep 16 1991 epiplot.uue
You can ftp seqaid from:
Host fly.bio.indiana.edu
Location: /molbio/ibmpc
FILE -rw-r--r-- 324175 May 14 1991 seqaidfd.uue
Host genbank.bio.net
Location: /pub/dos
FILE -rw-rw-r-- 6167 Oct 26 1989 seqaid.doc
FILE -rw-rw-r-- 324175 Jul 14 1989 seqaidfd.uue
Host nic.funet.fi
Location: /pub/sci/molbio/msdos
FILE -rw-r--r-- 251259 Feb 3 00:00 seqaid.exe
FILE -rw-rw-r-- 305448 Jun 23 1991 seqaid37.shar
FILE -rw-r--r-- 73370 Feb 3 00:00 seqaidfd.exe
There is no ftp site for Tsites that I know of, you can obtain it
for free by writing to:
MedImmune, Inc
19 Firstfield Rd.
Gaithersburg, MD 20878 (USA)
Kudos go to the authors and Dan Davison, Don Gilbert and Rob Harper for the
ftp sites.
Best of luck,
Dan Jacobson
danj at chablis.gwu.edu
