In article <35748 at uflorida.cis.ufl.edu>, beatriz at pine.circa.ufl.edu (Beatriz Gonzalez-Yanes) writes:
>Dear netters,
>I imagine this question has been asked before, but I usually don"t
>read this group. My boss is willing to buy a program for the PC (386)
>that given a sequence, would draw a map of it. We would like one that
>could make linear or circular vectors with the corresponding
>restriction sites to scale. It can either be a DOS or Windows program.
>Of course, we would also be interested in a shareware version.
>>Thanks for any help,
>>Beatriz.
You may want to look at either "Clone3" ($300) or "Plasmid Map Enhancer"
($200) from Scientific & Educational Software, PO Box 440, State Line, PA,
17263 (717-597-5307). They have demo disks available.
Basically, Clone3 is a sequence/clone manipulator program. You can enter
sequence data, determine restriction sites, restrict a circular molecule &
ligate a fragment into it & have the RE sites rearranged appropriately,
etc. Although it does print out smooth plasmid circles, the print is
somewhat crude (comes out as a series of attached squares).
I guess that's why they came out with Plasmid Map Enhancer which produces
manuscript-quality plasmid figures/text, can enter sequence data too, but
doesn't let you do the cloning/ligation that Clone3 allows. You can bring
in a map generated with Clone3 and print it with Plasmid Map Enhancer, or
beautify it, to get a better quality presentation.
Take a look at the demo's, they're free.
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