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Large Scale Sequence Alignments, ~200 kb

Mick Jones m.d.jones at ic.ac.uk
Fri Sep 20 07:00:28 EST 2002


I'm trying to align some large genomic sequences, 200 kb in length, and the
DNA Star
Megalign program cannot handle it. I need to be able to match sequences from
the mouse genome,
from Ensembl, to large clone sequences from GenBank, to try to fill in
the holes in the genome sequence.

Can anybody offer advice on what programs I could use?

Many thanks


Michael D Jones, BSc, PhD
Head Genomics Core Laboratory
MRC Clinical Sciences Centre
Hammersmith Hospital Campus
London, UK

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