IUBio

3-point data

Danielle et jean Thierry-Mieg mieg at beta.crbm.cnrs-mop.fr
Wed Nov 17 12:06:27 EST 1999


eg. A_not_B:   W 20 X 10 Y 5 Z

in this example how does ACE know if the W-X interval contained 20
recombinants out of 200, 2000, or 2 billion individuals scored??  Surely
this is important?  or??

what am I missing here?

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the way multipoint data is used is for ordering genes close to each other
the 3 p data gives the true order of the 3 genes, and with great sampling error
the relative distance ab/bc
what it does NOT give is the scale, i.e. is it .01 or .1 centimrogan

the scale is given by counting more 2 point data on say ther api AC
 i mean the pair AC

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