Position Title: Postdoctoral Research Position
Location: Dept. of Biochemistry, University of Alberta, Edmonton,
Alberta, Canada.
Salary: In accordance with current CIHR rates (approximately
$35,000/annum).
Project Description. A postdoctoral position is available to study pH
regulation and/or the Na+/H+ exchanger of yeast S. pombe Sod2. Likely
projects will include one or more of (1), the study of amino acid
residues involved in cation binding and transport, (2), determination
of the topology of the protein, (3), alanine or cysteine scanning
mutagenesis of the protein (4) identification, localizaton and
characterization of novel Na+/H+ exchanger proteins of S. pombe. (See
Biochemistry 37:8282).
Eligibility Requirements. Applicants should have experience in growth
and transformation of yeast strains. Applicants should have
experience in biochemistry and molecular biology. They should also be
able to work independently. Applicants are expected to have at least 1
-2 publications in a reputable journals with an impact factors greater
than 1.0. Applicants should have received their Ph.D. within the last
2 years (preferred) or within a maximum of 3 years.
Duration: The position is available in Canada in the city of Edmonton,
Alberta beginning immediately or April 1, 2004. It is renewable for a
second year with the possibility of a third year of renewal. A one
page summary of scientific interests should be provided along with a
curriculum vitae and names of 2-3 references to:
Contact Dr. L. Fliegel
Dept. of Biochemistry
University of Alberta
347 Medical Science Bldg.
Edmonton, Alberta
Canada, T6G 2H7
lfliegel at ualberta.ca
Ph (780) 492-1848, Fax (780) 492-0886
http://www.biochem.ualberta.ca/content.php?id=2&faculty=6
Selected Recent Publications:
Rakhilya Murtazina, Brenda J. Booth, Bonnie L. Bullis, Dyal N. Singh
and L. Fliegel (2001) Functional analysis of polar amino acid residues
in membrane associated regions of the NHE1 isoform of the Na+/H+
exchanger. Eur. J. Biochem. 268:4674-4685. # 11532004
Pavel Dibrov Paul G. Young and Larry Fliegel (1998) Conserved His and
Asp residues are essential for activity of sod2, the Na+/H+ exchanger
of fission yeast. Biochemistry 36:8282-8288.
Pavel Dibrov and Larry Fliegel (1998) Comparative molecular analysis
of Na+/H+ exchangers: A unified model for Na+/H+ antiport? FEBS
Lett. 424:1-5.
--
Dr. L. Fliegel,
Professor and Heritage Foundation
for Medical Research Scientist
Dept. of Biochemistry
Faculty of Medicine
347 Medical Science Bldg.
University of Alberta
Edmonton, AB
Canada, T6G 2H7
780 492 1848
Fax 492 0886
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