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Revised annotation of the S. cerevisiae genome

Anand Sethuraman anand at genome.stanford.edu
Thu Jul 31 11:34:49 EST 2003


Dear Colleagues,

	SGD has revised the current annotation to the S. cerevisiae
genome.  This revised annotation has two notable components:

	1. The addition of 354 ORFs, as reported in various literature
including Brachat et al. (PubMed 12844361), Kessler et al. (PubMed
12566404), Kumar et al. (PubMed 11753363), and Oshiro et al. (PubMed
12176929). For a complete list of these new ORFs, please go to

  http://www.yeastgenome.org/newORFs.html

	2. The classification of all ORFs, as "Verified",
"Uncharacterized", or "Dubious", according to the degree of certainty
that each ORF actually encodes a protein. For a more complete
description these ORF types, please go to SGD Glossary Terms page at:
http://www.yeastgenome.org/help/glossary.html.  These classifications
were made based on three large scale comparative genomics studies
(Kellis et al. (PubMed 12748633), Cliften et al. (PubMed 12775844),
and Brachat et al. (PubMed 12844361)) and our own survey of available
literature. SGD considers this a working hypothesis and welcomes input
from the yeast community on these classifications. For a complete list
of the 820 "Dubious" ORFs, please go to
http://www.yeastgenome.org/dubiousORFs.html

Best regards,
Anand

*****************************************************
Anand Sethuraman Ph. D., Scientific Curator
Saccharomyces Genome Database
Department of Genetics
Stanford University School of Medicine
Stanford, CA 94305-5120
Ph: (650)724-9959    Fax:(650)723-7016
E-mail: yeast-curator at yeastgenome.org
http://www.yeastgenome.org/
******************************************************

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