>> Wenyi writes,
> Dear yeast community,
> I have a what might appear to be galactically stupid question: is
> MEC1 essential for viability in budding yeast? I have seen different
> reports and am genuinely confused. I'd appreciate it if someone could
> explain to me.
MEC1 is indeed essential. However, its lethal phenotype can be suppressed by deletion of a second gene, SML1.
Thus, in a strain that is already sml1-minus, MEC1 would appear to be non-essential.
--
-susan
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