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Is MEC1 essential for viability or not?

Matthias Bureik mabu at rz.uni-sb.de
Wed Sep 26 01:39:55 EST 2001

Dear Wenyi,

I am not working on MEC1 but did you check the Saccharomyces genome
database? (http://genome-www4.stanford.edu/cgi-bin/SGD/locus.pl?locus=mec1)
They say that the null mutant is inviable but overproduction of Rad53p
rescues some mec1 alleles. Do you have reason to doubt this?

Best wishes


>     I have a what might appear to be galactically stupid question: is
> MEC1 essential for viability in budding yeast?  I have seen different
> reports and am genuinely confused. I'd appreciate it if someone could
> explain to me.
> Thanks!
> Wenyi

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