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[pombelist] Fission yeast evolution (fwd)

Francis Ouellette francis at cmmt.ubc.ca
Thu Aug 16 09:14:39 EST 2001

forwarding an interesting note from Susan on pombe and cerevisiae.



| B.F. Francis Ouellette                       francis at cmmt.ubc.ca | 
| Director, Bioinformatics Core Facility       Tel: (604) 875-3815 | 
| Centre for Molecular Medicine & Therapeutics Fax: (425) 740-6978 | 
| Vancouver, BC Canada            http://www.cmmt.ubc.ca/ouellette |

---------- Forwarded message ----------
Date: Wed, 15 Aug 2001 18:23:15 -0700
From: S L Forsburg <forsburg at salk.edu>
To: pombelist at sanger.ac.uk
Subject: [pombelist] Fission yeast evolution

Hi everyone,
You might be interested in a paper in the new issue of SCIENCE, 
entitled "Molecular Evidence for the Early Colonization of Land by 
Fungi and Plants"
  by Heckman DS, Geiser DM, Eidell BR, Stauffer RL, Kardos NL, Hedges SB.
   Science. 2001 Aug 10;293(5532):1129-33.

The paper argues that the divergence of the fungi is much earlier 
than previously expected, using an analysis of multiple proteins in 
the databases.  Of most interest to us is that the divergence between 
archaeascomycetes (eg, pombe) and ascomycetes (eg, cerevisaie) is 
placed at 1144 million years--a significantly longer time ago than 
previous estimates!  (For comparison, the divergence between S. 
cerevisiae and Candida albicans is now estimated at 841 My.)

I have confirmed with the senior author, Blair Hedges, that pombe 
sequences were the major taxon representing archaeascomycetes.

In other words, our favorite yeast is REALLY OLD!


Susan L Forsburg PhD   Associate Professor
Molecular & Cell Biology Laboratory
The Salk Institute for Biological Studies
10010 N Torrey Pines Rd
La Jolla, California 92037 USA

vox: + 1 858 453 4100 x1341
fax: + 1 858 457 4765

forsburg at salk.edu

Science is built up of facts, as a house is built of
stones; but an accumulation of facts is no more a science
than a heap of stones is a house.
          Henri Poincare, Science and Hypothesis (1905)



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