Applications for postdoctoral and research assistant positions are immediately available in my laboratory. Candidates should be highly motivated and have good expertise in molecular biology, biochemistry and/or cell biology techniques.
Current work underway in the laboratory focus on studying biogenic steps of G- protein coupled receptors and phosphoinositide signaling in neuronal cells (http://www.mcw.edu/pharm/faculty/ferreira.html). We have been particularly interested in investigating i) the molecular mechanisms underlying the function of a new neuronal signaling pathway mediated by a novel PI-phospholipase C (e.g. Ferreira, P. et al. (1994). J. Biol. Chem., 269, 3129; Ferreira, P. et al. (1993) Proc. Natl. Acad. Sci. USA, 90, 6042) and, ii) the molecular machinery involved in the intracellular processing and trafficking of homologous G-protein coupled receptors in highly polarized neuronal cells (e.g. Ferreira et al. (1998), J. Biol. Chem. 273, 24676; Ferreira, P. et al. (1997) Proc. Natl. Acad. Sci. USA, 94, 1556; Ferreira, P. et al. (1996) Nature 383, 637; Ferreira, P. et al. (1995) J. Biol. Chem. 270, 23179). In addition, we are using our studies as a model system to study widespread homol!
ogous molecular mechanisms in other biological systems and understand the molecular pathogenesis underlying certain inherited neurological disorders in humans which ultimately lead to the degeneration of selective neurons in the CNS. The laboratory and institution are equipped with state-of-art facilities and operate in an outstanding research environment. The prospective candidate is expected to participate in campus-wide interactive programs such as seminars and ultimately, present his\her research results at international meetings and publish in top-rated scientific journals. Salary is based on experience and NIH guidelines.
Candidates with an overall interest in neurobiology are invited to apply and should send their CV, summary of their past research experience and future goals, and three reference letters directly to:
Paulo A. Ferreira, Ph.D.
Medical College of Wisconsin
Pharmacology Department
8701 Watertown Plank Road
Milwaukke, WI 53226
Phone: 414-456-8877
Fax: 414-456-6545;
Email: ferreira at post.its.mcw.edu
<bold><color><param>0000,0000,8080</param>Paulo A. Ferreira, Ph.D.
Assistant Professor
</color></bold><color><param>8080,0000,0000</param>Medical College of
Wisconsin
Pharmacology Department
8701 Watertown Plank Road
Milwaukee, WI 53226
FAX: 414-456-6370 // -6545
Phone: 414-456-8877 // -8267; Lab: -8043</color>
