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postdoctoral position available

Judith Berman judith at biosci.cbs.umn.edu
Tue Dec 1 07:24:36 EST 1998


A Postdoctoral position is available to investigate telomere function and the 
mechanisms of epigenetic silencing in S. cerevisiae in the laboratory of Judith 
Berman at the University of Minnesota.  We are looking for an enthusiastic 
postdoctoral colleague interested in the biochemistry and molecular biology of 
chromatin structure, especially as it relates to telomere functions. Our lab is 
trying to understand how silent chromatin is established and maintained and how 
different aspects of telomere function are regulated.  In particular, the roles 
of Chromatin Assembly Factor I, histone acetylation and nonsense-mediated mRNA 
decay in telomeric silencing and other telomeric functions are currently being 
explored.  Some references to our recent work are appended to this note.  
We are looking for an independent, creative, and energetic individual who can 
bring her or his own skills to the lab to synergize withexisting investigative 
work in the group.  

The successful candidate is expected to be (in order of importance)
 (1) a socially responsible lab member able to interact well and easily with 
other lab members 
(2) hard working and self motivated, 
(3) published, 
(4) smart, and 
(5) knowledgeable about molecular biology and biochemistry

To be considered, applicants must hold a Ph.D. degree or foreign equivalent and 
will preferably hold U.S. citizenship or Permanent Resident status.  Applicants 
should send a curriculum vitae, a brief statement of research interests and 
experience, and the names, addresses, email addresses and telephone numbers of 
three references.  

Direct applications to:  

Dr. Judith Berman-- CBS 076
College of Biological Sciences
220 Biological Sciences Center
1445 Gortner Avenue
St. Paul, MN 55108

email applications should be sent to:  annec at biosci.cbs.umn.edu

Relevant References
Enomoto, S. and Berman, J.  1997.  Chromatin Assembly Factor 1 contributes to 
the maintenance of silencing at the silent mating type loci.  Genes & Dev.12: 
Enomoto, S., P.D. McCune-Zierath, M. Gerami-Nejad, M.A. Sanders and J. Berman.  
1997.  RLF2, a subunit of yeast chromatin assembly factor I, is reqauired for 
telomeric chromatin function in vivo.  Genes & Dev. 11: 358-370. 
Lew, JE, S Enomoto & J Berman  (1998) Telomere length regulation and telomeric 
chromatin require  the nonsense-mediated mRNA decay pathway. Mol. Cell. Biol. 
18: 6121-6130.
Johnston, S, JE Lew & J Berman  (1998) Gbp1p, a protein with RNA recognition 
motifs, binds single-stranded telomeric DNA and changes its binding specificity 
upon dimerization. Mol. Cell. Biol., 19 (1): in press.

Judith Berman
Associate Professor
College of Biological Sciences
220 Biological Sciences Center
University of Minnesota
St. Paul, MN 55108

TEL:  612-625-1971
FAX:  612-625-1738
email:  judith at biosci.cbs.umn.edu 

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