UNIVERSITY OF MINNESOTA
POSTDOCTORAL POSITION TO STUDY TELOMERES AND SILENCING
A Postdoctoral position is available to investigate telomere function and the
mechanisms of epigenetic silencing in S. cerevisiae in the laboratory of Judith
Berman at the University of Minnesota. We are looking for an enthusiastic
postdoctoral colleague interested in the biochemistry and molecular biology of
chromatin structure, especially as it relates to telomere functions. Our lab is
trying to understand how silent chromatin is established and maintained and how
different aspects of telomere function are regulated. In particular, the roles
of Chromatin Assembly Factor I, histone acetylation and nonsense-mediated mRNA
decay in telomeric silencing and other telomeric functions are currently being
explored. Some references to our recent work are appended to this note.
We are looking for an independent, creative, and energetic individual who can
bring her or his own skills to the lab to synergize withexisting investigative
work in the group.
The successful candidate is expected to be (in order of importance)
(1) a socially responsible lab member able to interact well and easily with
other lab members
(2) hard working and self motivated,
(3) published,
(4) smart, and
(5) knowledgeable about molecular biology and biochemistry
To be considered, applicants must hold a Ph.D. degree or foreign equivalent and
will preferably hold U.S. citizenship or Permanent Resident status. Applicants
should send a curriculum vitae, a brief statement of research interests and
experience, and the names, addresses, email addresses and telephone numbers of
three references.
Direct applications to:
Dr. Judith Berman-- CBS 076
College of Biological Sciences
220 Biological Sciences Center
1445 Gortner Avenue
St. Paul, MN 55108
email applications should be sent to: annec at biosci.cbs.umn.edu
Relevant References
Enomoto, S. and Berman, J. 1997. Chromatin Assembly Factor 1 contributes to
the maintenance of silencing at the silent mating type loci. Genes & Dev.12:
219-232.
Enomoto, S., P.D. McCune-Zierath, M. Gerami-Nejad, M.A. Sanders and J. Berman.
1997. RLF2, a subunit of yeast chromatin assembly factor I, is reqauired for
telomeric chromatin function in vivo. Genes & Dev. 11: 358-370.
Lew, JE, S Enomoto & J Berman (1998) Telomere length regulation and telomeric
chromatin require the nonsense-mediated mRNA decay pathway. Mol. Cell. Biol.
18: 6121-6130.
Johnston, S, JE Lew & J Berman (1998) Gbp1p, a protein with RNA recognition
motifs, binds single-stranded telomeric DNA and changes its binding specificity
upon dimerization. Mol. Cell. Biol., 19 (1): in press.
Judith Berman
Associate Professor
College of Biological Sciences
220 Biological Sciences Center
University of Minnesota
St. Paul, MN 55108
TEL: 612-625-1971
FAX: 612-625-1738
email: judith at biosci.cbs.umn.edu
