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Research in Telomeres

Lustig, Arthur J. alustig at mailhost.tcs.tulane.edu
Tue Aug 25 08:47:43 EST 1998


A funded postdoctoral position is available to study telomere structure and
function

	Two postdoctoral positions are available to investigate telomere
dynamics in Saccharomyces cerevisiae in the laboratory of Arthur J. Lustig
at Tulane University Medical Center. We have had a long-standing
fascination in telomere structure and function and are currently focusing
on two broad areas:

	1) The mechanisms of nucleation and inheritance of telomeric
silencing (e.g., Lustig et al.1996 "Tethered Sir3p nucleates silencing at
telomeres and internal loci in Saccharomyces cerevisiae".MCB 16: 2843,
1996; Lustig, AJ. 1998 "Mechanisms of silencing in Saccharomyces
cerevisiae".  Curr. Opin Genet. and Develop 8: 233., Park et al 1998
'Sir3p domains involved in the initiation of telomeric silencing in
Saccharomcyes cervisiae', November issue of Genetics);
	and
	2) The mechanism of telomere size maintainence (e.g. Li and
Lustig," A novel mechanism for telomere size control in Saccharomyces
cerevisiae" Genes Dev. 10: 1310; Polotnianka et al, 1998 "The yeast Ku
heterdomer is essential for protection of the telomere against nucleolytic
and recombinational activities." Current Biology 8: 831.)

	Also see my web page at http://www.tulane.edu/~biochem/lustig.htm

	Candidates should have a background in molecular biology and/or
genetics.  Background in yeast is preferable but not required.

	Interested candidates should send their c.v. either by e-mail, fax,
or mail to the address listed below.

Arthur J. Lustig
Associate Professor
Department of Biochemistry SL43
Tulane University Medical Center
1430 Tulane Avenue
New Orleans, LA 70112
phone: 504-584-3688
fax: 504-584-2739




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