Jon wrote:
>Dear Yeasties,
> a friend has just asked me where they can find a list describing all the
>common mutations in marker genes at the DNA level (eg. what nucleotides
>the ura3-52 deletion encompasses). Problem is I do not know of such a
>site/reference. Does anyone out in YeastLand know of such a list?
>>Jon Swaffield
>
Dear Jon,
I, too was looking for such list, and have posted to this newsgroup, but
I haven't got any answer yet. I wish someone make a list and post on the
Internet. FYI, ura3-52 is not deletion, but Ty insertion somewhere in
the N-terminal half of URA3. However, ura3-52 makes a shorter transcript
than URA3 because of either frameshift mutation or possible introduction
of stop codon by Ty transposon. Another common marker leu2-3,112 has two
point mutations in LEU2 gene. That's all I know for sure.
___________________________________
Namjin Chung
Rm. 213 MSRB, Box 3345
Program in Molecular Cancer Biology
Duke University Medical Center
Durham, NC 27710
nc1 at acpub.duke.edu
___________________________________
