>I then did a blastp with with the E. coli mutT AA sequence against the
>complete yeast genome AA sequences, a 'blastable' database we maintain
>and update at NCBI, on our blast server:
>>http://www.ncbi.nlm.nih.gov/BLAST/>>and didn't pick up too much. The alignment of the best Sc score
>(YBR111c; protein ecoded by EMBL/GenBank Accession Number Z35980) and
>the mutT is shown below. Nothing worth writing home about, although
>some domains may be conserved. The dot plot between these two
>sequences shows that something may be there as well.
YBR111c has recently been named YSA1 and reported as an ADP-ribose hydrolase
by Bessman et al. JBC 271: 25059 1996. Interesting, since, as far as I know,
there is no ADP-ribosylation in S.c. Maybe involved in NAD/H degradation
Preston Garrison, Ph.D.
garrisonp at uthscsa.edu
Univ of Texas Health Sci Ctr
San Antonio, Tx 78284-7760 USA