IUBio

Hexamine Cobalt cytotoxicity?

Anthony Tomlinson tomlinson at pplros.demon.co.uk
Fri Oct 25 08:52:17 EST 1996


I have been reading a paper by Kovacic et al (NAR 23 (19), 3999-4000,
1995)
where Co(NH3)6Cl3 was used to protect large DNA from shearing.  Does
anyone know
anything about the cytotoxicity of this compound, especially in mammalian
cells
(I'm thinking about YAC transfection and also microinjection).

Thanks,

Anthony.



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