Postdoctoral Position: A postdoctoral position is available immediately
to study the trafficking of phospholipids in yeast using fluorescent-
labeled phospholipids. Our laboratory has demonstrated that
fluorescent-labeled phospholipids can be used to identify and study the
mechanisms for phospholipid internalization in Saccharomyces
cerevisiae (Kean et al., JCB, 123:1403-1419, 1993). Subsequently, we
have developed a novel screen to isolate mutants in the internalization of
NBD-labeled phosphatidylethanolamine which involves transmembrane
transfer (flip-flop) across the plasma membrane. Mutant strains
representing three complementation groups have been isolated. The
successful candidate will participate in the identification of additional
complementation groups, cloning the responsible genes by
complementation, and characterization of the gene products. This
position will be funded for an initial period of two years by an NIH
grant. A strong background in yeast genetics, cell and molecular
biology is essential. Please respond with an application letter and C.V.
by Email, FAX or letter to: Dr. Wylie Nichols, Department of
Physiology, Emory University School of Medicine, Atlanta GA 30322.
Email: wnichols at physio.emory.edu; FAX: (404) 727-2648;
Telephone: (404) 727-7422. Emory University is an Affirmative Action/
Equal Opportunity Employer.