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Postdoctoral Position

Wylie Nichols wnichols at physio.emory.edu
Wed Nov 1 16:20:00 EST 1995


Postdoctoral Position:  A postdoctoral position is available immediately 
to study the trafficking of phospholipids in yeast using fluorescent-
labeled phospholipids.  Our laboratory has demonstrated that 
fluorescent-labeled phospholipids can be used to identify and study the 
mechanisms for phospholipid internalization in Saccharomyces 
cerevisiae (Kean et al., JCB, 123:1403-1419, 1993).  Subsequently, we 
have developed a novel screen to isolate mutants in the internalization of 
NBD-labeled phosphatidylethanolamine which involves transmembrane 
transfer (flip-flop) across the plasma membrane.  Mutant strains 
representing three complementation groups have been isolated.  The 
successful candidate will participate in the identification of additional 
complementation groups, cloning the responsible genes by 
complementation, and characterization of the gene products.  This 
position will be funded for an initial period of two years by an NIH 
grant.  A strong background in yeast genetics, cell and molecular 
biology is essential.  Please respond with an application letter and C.V. 
by Email, FAX or letter to:  Dr. Wylie Nichols, Department of 
Physiology, Emory University School of Medicine, Atlanta GA 30322.  
Email:  wnichols at physio.emory.edu;  FAX:  (404) 727-2648;  
Telephone:  (404) 727-7422.  Emory University is an Affirmative Action/
Equal Opportunity Employer.




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