IUBio

Are there yeast homologs of p53?

Bryan Ford fordb at AVA.BCC.ORST.EDU
Mon Jun 5 15:28:06 EST 1995


I'm am curious why purported "overexpression" of the vertebrate tumor 
suppressor kills yeast (S. cerevisiae). Are one or another of the 
functional domains of p53 homologously present in budding yeasts? My very 
recent genbank+EMBO+PIR etc. data base search showed nothing for budding 
yeasts but did show suppressor genes (dehydrogenases) for p53 growth 
suppression in fission yeast (S. pombe).  

                         Thanks in advance,
Bryan L. Ford
Marine/Freshwater Biomedical Center
Wiegand Hall
Oregon State University
Corvallis, Oregon  97331-6602



More information about the Yeast mailing list

Send comments to us at biosci-help [At] net.bio.net