A postdoctoral position is available at Dartmouth Medical School to study
nucleocytoplasmic export of RNA in Saccharomyces cerevisiae. A genetic screen
has identified a large number of complementation groups encoding gene products
required for efficient export of mRNA from the nucleus. Several of these
encode nuclear pore complex components (see JCB, 129:939-955, 1995 and Mol
Biol Cell, 6:401-417, 1995) while others encode components of the
Gsp1p/Rna1p/Prp20p small GTPase system involved in nucleocytoplasmic exchange.
Qualifications include experience in the basic techniques of molecular biology.
Prior experience with yeast or with fluorescence microscopy is an asset.
The postodc will be part of a group engaged in identifying additional gene
products important for RNA export and in determining the role in RNA export
performed by various proteins. Additional studies are directed at examining
possible mechanisms and situations where export of mRNA is regulated and in
determining whether different gene products are required for the
nucleocytoplasmic transport of different classes of RNA.
For additional information, contact
Dr. Charles Cole
Department of Biochemistry
Dartmouth Medical School
7200 Vail Building
Hanover, NH 03755
email Charles.Cole at Dartmouth.edu
To apply for the position, please send a copy of your CV and the names of three
references who can provide a letter of recommendation.