Medical Research Council
Human Genetics Unit
EC Human Capital Mobility Post-Doc
Up to 2 years funding available to work with
Dr Robin Allshire on:
"Silencing at the fission yeast centromeres as a means to
isolate components of the kinetochore complex"
The Successful applicant will further characterise mutants
defective in centromere silencing and chromosome segregation.
Experience in molecular biology or yeast genetics and especially
immunoprecipitation/protein purification would be an advantage.
For background reading see:
Allshire RC et al (1994) Position effect variegation at the fission yeast
centromeres Cell 76:157-170
Nimmo,R.E. et al (1994) Telomere associated chromosome breakage in
fission yeast results in variegated expression of adjacent genes EMBO J
Allshire R.C et al (1995) Mutations derepressing silent centromeric
domains in fission yeast disrupt chromosome segregation in fission yeast.
Genes and Development 9 218
Applicants must be nationals of a community member state or
associated state other than the UK and must not have carried out work in
the UK for more than 2 years prior to the submission of an application.
In the first instance applicants should contact Dr Robin Allshire at
MRC Human Genetics Unit, Western General Hospital, Crewe Road,
Edinburgh EH4 2XU,SCOTLAND, UK.
or Tel (44)-31-343-2620 Fax: (44)-31-343-2620 or Email
robin at hgu.mrc.ac.uk